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Updated: Jun 8, 2025

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
Epidemiological Characteristics of Dengue Fever - China, 2005-2023
Zhuowei Li1, Xiaoxia Huang1, Aqian Li1
1National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, NHC Key Laboratory of Biosafety, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Diseases Control and Prevention, Beijing, China.
Introduction:
The global incidence of dengue fever has increased significantly over the past two decades, and China faces a significant upward trend in dengue control challenges.
Methods:
Data were obtained from China's NNDRS from 2005 to 2023. Joinpoint regression software was used to analyze temporal trends, while SaTScan software was used to analyze spatial, seasonal, and spatiotemporal distributions. ArcGIS software was used to visualize clusters.
Results:
A total of 117,892 dengue cases were reported from 2005 to 2023, with significant fluctuation in annual reported cases. Dengue was not endemic in China. Autochthonous outbreaks most likely occurred in the southwestern, southeastern coastal, and inland areas of China. These outbreaks have occurred between June and November, generally peaking in September or October, around epidemiological week (EW) 40.
Conclusions:
Dengue challenges in China are increasing. Timely case monitoring, proactive control interventions, and staff mobilization should be implemented before June to ensure a timely response to autochthonous outbreaks.
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