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The Frequency of Occurrence of Strabismus in Infants Post Lensectomy
Jonas Akambase1, Michael Barkley1, Richa Sharma1
1Ophthalmology, Queensland Children's Hospital, Brisbane, AUS.
Insights
Strabismus, often esotropia, is common in infants after congenital cataract surgery, especially following unilateral procedures and in those under six months old. Early monitoring of strabismus and interocular visual acuity is vital for preventing amblyopia.
Area of Science:
- Ophthalmology
- Pediatric Surgery
- Strabismus Research
Background:
- Congenital cataracts require early surgical intervention, typically lensectomy.
- Post-lensectomy visual development in infants is complex and can be affected by various ocular conditions.
- Strabismus and visual acuity deficits are potential complications following pediatric cataract surgery.
Purpose of the Study:
- To identify and characterize the incidence of strabismus in infants following lensectomy for congenital cataracts.
- To analyze the interocular visual acuity (IOVA) differences in this patient cohort.
- To determine risk factors associated with post-lensectomy strabismus.
Main Methods:
- Retrospective chart review of infants (<12 months) undergoing lensectomy between 2014-2021.
- Exclusion of cases with pre-existing strabismus.
- Analysis of strabismus types, age at surgery, and IOVA differences.
Main Results:
- 25% of 75 infants developed strabismus post-lensectomy, predominantly esotropia (74%).
- Unilateral cataract surgery and surgery before 6 months of age were associated with higher strabismus incidence.
- Significant IOVA differences were observed between strabismic and non-strabismic groups, and unilateral vs. bilateral surgery groups.
Conclusions:
- Strabismus, particularly esotropia, is a common outcome after congenital lensectomy, especially in unilateral cases and younger infants.
- Close monitoring of IOVA and strabismus is essential for timely intervention and amblyopia prevention in this population.
Abstract:
Purpose To identify and characterize incident cases of strabismus and interocular visual acuity among infants post lensectomy for congenital cataract. Method This was a single-centre retrospective chart review of all children aged less than 12 months who underwent lensectomy from 1st January 2014 to 1st January 2021. Cases were identified from theatre coding and electronic medical records. Cases with strabismus prior to cataract surgery were excluded. Results Seventy-five children (114 aphakic eyes) were included, 36 (48%) had unilateral cataract surgery while 39 (52%) had bilateral. The mean age at the time of cataract surgery was 3.0±2.5 months (range 1 - 10 months). The mean follow-up period was 41.2±22.8 months (range 2 -72 months). Nineteen out of 75 patients (25%) developed strabismus, most of whom (18 cases) had unilateral surgery. Out of the 19 strabismus cases recorded, esotropia was reported in 74% of the cases, followed by exotropia -16%, while esotropia associated with dissociated vertical deviation (DVD) and esotropia associated with inferior oblique each made up 5% of the population. Most children who developed strabismus [17 patients (89.5%)] had lensectomy prior to 6 months of age. A significant difference of 0.65 logMAR was recorded in the interocular visual acuity (IOVA) difference between the strabismic and non-strabismic groups, and the unilateral and bilateral lensectomy groups. Conclusion Strabismus, most commonly esotropia, is common after congenital lensectomy, particularly in those children who underwent unilateral cataract surgery, and in those less than 6 months of age. Monitoring IOVA and strabismus incidence post-cataract surgery is crucial for early intervention and amblyopia prevention.
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