Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

LncRNA FAM66C predicts poor prognosis in patients with lung adenocarcinoma and regulates cell proliferation and metastasis via miR-339-3p.

Journal of cardiothoracic surgery·2025
Same author

Immune Tolerance Regulation Is Critical to Immune Homeostasis.

Journal of immunology research·2025
Same author

Silencing the lncRNA EBLN3P Improves Prognosis in Patients with Invasive Breast Cancer by Directly Targeting miR-144-3p.

Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer·2024
Same author

Unlocking Immunity: Innovative prostate cancer vaccine strategies.

International immunopharmacology·2024
Same author

Macrophage dynamics in prostate cancer: Molecular to therapeutic insights.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2024
Same author

LncRNA SNHG1 serves as a biomarker for systemic lupus erythematosus and participates in the disease progression.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica·2024

Related Experiment Video

Updated: Jun 8, 2025

The Isolation and Culture of Primary Epicardial Cells Derived from Human Adult and Fetal Heart Specimens
08:57

The Isolation and Culture of Primary Epicardial Cells Derived from Human Adult and Fetal Heart Specimens

Published on: April 24, 2018

7.8K

Research Progress on Epicardial Repair After Myocardial Injury.

Guohua Li1, Zongquan Yan2, Lei Han3

  • 1From the Jinzhou Medical University, Jinzhou, China.

Cardiology in Review
|November 6, 2024
PubMed
Summary

The epicardium aids heart repair after injury through activation and transformation. Understanding these processes could lead to new cardiac regeneration therapies.

More Related Videos

In Vitro Culture of Epicardial Cells From Mouse Embryonic Heart
06:31

In Vitro Culture of Epicardial Cells From Mouse Embryonic Heart

Published on: April 27, 2016

7.4K
Author Spotlight: Cardiac Cell Transgenesis for Rapid Gene Screening
05:06

Author Spotlight: Cardiac Cell Transgenesis for Rapid Gene Screening

Published on: May 24, 2024

610

Related Experiment Videos

Last Updated: Jun 8, 2025

The Isolation and Culture of Primary Epicardial Cells Derived from Human Adult and Fetal Heart Specimens
08:57

The Isolation and Culture of Primary Epicardial Cells Derived from Human Adult and Fetal Heart Specimens

Published on: April 24, 2018

7.8K
In Vitro Culture of Epicardial Cells From Mouse Embryonic Heart
06:31

In Vitro Culture of Epicardial Cells From Mouse Embryonic Heart

Published on: April 27, 2016

7.4K
Author Spotlight: Cardiac Cell Transgenesis for Rapid Gene Screening
05:06

Author Spotlight: Cardiac Cell Transgenesis for Rapid Gene Screening

Published on: May 24, 2024

610

Area of Science:

  • Cardiology
  • Regenerative Medicine
  • Cell Biology

Background:

  • Myocardial injuries, like myocardial infarction, initiate complex biological responses.
  • The epicardium, a crucial outer layer of the heart, possesses regenerative potential.
  • Epicardial activation is key to cardiac repair mechanisms.

Purpose of the Study:

  • To review the mechanisms of epicardial activation following myocardial injury.
  • To highlight the role of the epicardium in cardiac repair.
  • To explore therapeutic implications for enhancing heart regeneration.

Main Methods:

  • Literature review focusing on epicardial activation post-myocardial injury.
  • Analysis of key cellular processes: epithelial-mesenchymal transition, proliferation, and migration.
  • Synthesis of current knowledge on epicardial function in cardiac repair.

Main Results:

  • Epicardial activation involves epithelial-mesenchymal transition, cell proliferation, and migration.
  • These transformations are critical for the heart's repair processes.
  • The epicardium's regenerative capacity is significant for post-injury recovery.

Conclusions:

  • The epicardium is pivotal in cardiac repair and regeneration.
  • Understanding epicardial dynamics offers potential for novel therapeutic strategies.
  • Targeting epicardial cell behavior could reduce heart disease morbidity.