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Updated: Jun 8, 2025

06:08
A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
Published on: March 21, 2025
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[Prostate cancer screening : to be recommended in 2024?]
Alexandrine Bosshart1, Frédéric Bacchetta2, Anne Boesch3
1Unisanté, Centre universitaire de médecine générale et santé publique, 1011 Lausanne.
Revue Medicale Suisse
|November 7, 2024
Summary
The Prostate Specific Antigen (PSA) blood test screens for prostate cancer in men aged 50-69. Using multiparametric MRI after a positive PSA can reduce biopsies and overdiagnosis risks.
Area of Science:
- Oncology
- Diagnostic Imaging
- Urology
Context:
- Prostate Specific Antigen (PSA) blood test is the sole screening method for prostate cancer.
- Screening is advised for men aged 50-69 within a shared decision-making framework.
- Overdiagnosis presents a significant risk associated with PSA screening.
Purpose:
- To outline the current recommendations and risks associated with Prostate Specific Antigen (PSA) screening.
- To explore strategies for mitigating the risks of overdiagnosis in prostate cancer screening.
- To highlight the role of advanced imaging in refining diagnostic pathways.
Summary:
- The Prostate Specific Antigen (PSA) test is the primary tool for prostate cancer screening, recommended for men aged 50-69.
- Screening decisions should involve patient-doctor consultation using decision aids due to overdiagnosis risks.
- Screening frequency is individualized based on risk factors, age, and family history.
- Multiparametric MRI (mpMRI) post-PSA test can decrease unnecessary biopsies, thereby reducing overdiagnosis.
Impact:
- Informed patient-doctor decision-making for prostate cancer screening.
- Potential reduction in unnecessary invasive procedures like biopsies.
- Improved accuracy and specificity in prostate cancer diagnosis.
- Mitigation of the harms associated with prostate cancer overdiagnosis and overtreatment.
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