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Unveiling Relationship Between Specific Domain, Intensity, and Dose of Physical Activity and Biological Age: A
Jundan Huang1, Shuhan Zhou1, Xiaoyang Li1
1Xiangya School of Nursing, Central South University, Changsha, China.
Summary
Engaging in transport-related walking and moderate-intensity physical activity (PA) is linked to a younger biological age (BA). Tailoring PA interventions by domain, intensity, and dose is crucial for effective age-delaying strategies.
Area of Science:
- Gerontology
- Exercise Physiology
- Public Health
Background:
- Previous research has examined physical activity (PA) intensity and domain independently concerning biological age (BA).
- A comprehensive understanding of how different types, intensities, and amounts of PA influence BA is lacking.
- This gap limits the development of precise, evidence-based interventions for age-delaying.
Purpose of the Study:
- To investigate and compare the associations between various domains, intensities, and doses of physical activity (PA) and biological age (BA).
- To identify specific PA characteristics that are most effective in promoting a younger biological age.
- To inform the design of targeted interventions aimed at mitigating biological aging.
Main Methods:
- Analysis of data from 5216 middle-aged and older adults (aged 45 and above).
- Comparison of the relationships between different domains (transport-related, leisure-time, work-related), intensities (moderate, vigorous), and doses of PA with biological age.
- Subgroup analysis was conducted for older adults.
Main Results:
- Transport-related walking and leisure-time moderate-intensity PA (MPA) were significantly associated with a younger BA.
- Work-related PA, regardless of intensity, did not show a significant association with younger BA.
- U-shaped dose-response relationships were observed for transport-related PA and leisure-time MPA with BA.
- In older adults, all intensities of PA were associated with a decreased BA.
Conclusions:
- The domain, intensity, and dose of physical activity (PA) are critical factors influencing biological age (BA).
- Transport-related walking and moderate-intensity leisure-time PA appear particularly beneficial for reducing biological age.
- These findings underscore the need to consider nuanced PA characteristics in developing effective age-delaying interventions.
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