Related Experiment Video
Updated: Jun 8, 2025
10:27
Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
24.5K
[Pediatric coeliac disease: Clinical features and diagnostic process]
Gonzalo Ortiz1, María Del Carmen Toca1, Mabel Mora1
1Comité de Gastroenterología, Grupo de Trabajo de Enfermedad Celíaca, Sociedad Argentina de Pediatría.
Archivos Argentinos De Pediatria
|November 7, 2024
Summary
Celiac disease, a global health issue affecting 1% of people, requires updated diagnostic guidelines. This consensus provides pediatricians with current recommendations on serological testing, biopsies, and genetic analysis for celiac disease.
Area of Science:
- Gastroenterology
- Immunology
- Pediatrics
Context:
- Celiac disease is a prevalent chronic condition impacting global public health.
- Recent advancements in serological testing reveal celiac disease's clinical diversity.
- Existing international guidelines necessitate periodic updates for accurate diagnosis.
Purpose:
- To update diagnostic criteria for celiac disease in pediatric patients.
- To provide expert consensus on serological determinations and biopsy indications.
- To guide pediatricians on classifying clinical forms and utilizing genetic studies.
Summary:
- This consensus, developed by the Celiac Disease Working Group of the Argentine Society of Pediatrics, addresses the definition, clinical classifications, and diagnostic methods for celiac disease.
- It emphasizes updated recommendations for serological tests, duodenal biopsies, histopathological classification, and the role of genetic studies in pediatric celiac disease diagnosis.
- The document aims to standardize and improve the diagnostic approach for celiac disease in children.
Impact:
- Enhances diagnostic accuracy for celiac disease in pediatric populations.
- Facilitates earlier and more precise identification of celiac disease.
- Supports evidence-based clinical decision-making for pediatricians managing celiac disease.
More Related Videos
Related Concept Videos
01:30Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
319
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
319
01:28Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
89
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
89
01:27Inflammatory Bowel Disease I: Ulcerative Colitis
143
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
143
01:30Serum Laboratory Studies, Stool Test, Breath Test
316
Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
316
01:23Gastritis III: Clinical Manifestations and Management
158
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
158
01:30Inflammatory Bowel Disease II: Crohn's Disease
186
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
186