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Biological functions and molecular mechanisms of LINC01116 in cancer
Ke Shi1, Xue-Ying Wang2,3, Li-De Huang4
1Department of Thoracic Surgery, Beilun District People's Hospital of Ningbo, Ningbo City, China.
Abstract:
LINC01116, a long non-coding RNA (lncRNA), serves as an important regulator in the progression of cancer cells and has attracted increased attention in biological fields. It is overexpressed in various cancer cells and is significantly correlated with cancer development and poor prognosis in cancer patients. Moreover, LINC01116 regulates the gene expression of various cancers through intricate pathways, such as sponging the microRNAs or other non-genic manners. These signaling pathways greatly affect the cancer's biological functions, including cell growth, migration, invasion, and chemoresistance. Hence, LINC01116 may serve as a prognostic biomarker and therapeutic target for human cancer. This paper summarizes the current evidence regarding the biological functions and molecular mechanisms of LINC01116 in the progression of cancer, providing theoretical references for LINC01116-related cancer treatment in the future.
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