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Updated: May 5, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Surgical ablation of atrial fibrillation: Rationale and technique
1Department of Cardiothoracic Surgery, Division of Cardiac Surgery University of Pittsburgh Medical Center, Pittsburgh, USA.
Insights
The Cox maze procedure offers the highest long-term success for atrial fibrillation treatment. This review details the surgical approach, focusing on effective lesion creation and complication avoidance.
Area of Science:
- Cardiovascular Surgery
- Cardiac Electrophysiology
Background:
- Atrial fibrillation (AF) is a common arrhythmia with significant morbidity.
- The Cox maze procedure is a leading surgical treatment for AF, especially in persistent forms.
- Surgical ablation for AF can be performed concomitantly with other cardiac surgeries.
Purpose of the Study:
- To review the anatomic basis of surgical ablation for atrial fibrillation.
- To highlight key technical aspects and potential pitfalls of the Cox maze procedure.
- To guide surgeons in achieving effective atrial fibrillation ablation and minimizing complications.
Main Methods:
- Anatomical review of the atrial substrate for surgical ablation.
- Discussion of technical nuances for Cox maze procedure execution.
- Analysis of strategies to prevent complications like pacemaker implantation.
Main Results:
- The Cox maze procedure demonstrates superior long-term efficacy for atrial fibrillation compared to other modalities.
- Concomitant surgical ablation offers a valuable treatment option during cardiac surgery for other conditions.
- Proper technique is crucial for creating effective lesions and ensuring rhythm control.
Conclusions:
- The Cox maze procedure is the most effective treatment for atrial fibrillation, particularly persistent types.
- Understanding surgical anatomy and technique is essential for successful atrial fibrillation ablation.
- Avoiding complications and optimizing lesion efficacy are key goals in surgical AF treatment.
Abstract:
The Cox maze procedure is the most effective treatment for atrial fibrillation with the best long-term success rate compared to any other treatment modality, particularly in persistent and long-standing persistent atrial fibrillation. Cardiac surgeons have an unparalleled opportunity to treat atrial fibrillation as a concomitant operation during the treatment of ischemic or valvular disease. In addition, there are many options for surgical ablation of atrial fibrillation. In this review, we share the anatomic basis for surgical atrial fibrillation ablation, focusing on the Cox maze procedure and discuss some key technical points and common pitfalls to provide an effective ablation of atrial fibrillation. These include a discussion of avoidance of pacemaker implantation and other complications, and also how to produce the most effective lesions from a rhythm standpoint.

