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Updated: Jun 8, 2025

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Using Microarrays to Interrogate Microenvironmental Impact on Cellular Phenotypes in Cancer
Published on: May 21, 2019
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APMIS focus issue 2024-The microenvironment in human disease
Peter Østrup Jensen1,2,3, Mads Lichtenberg1
1Department of Clinical Microbiology, Copenhagen University Hospital.
Summary
No abstract available in PubMed .
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Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
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