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Related Concept Videos

Asthma-I: Introduction01:29

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma-II: Pathophysiology and Classification01:26

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
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Asthma: Pathogenesis and Management01:20

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
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Asthma and Memory Function in Children.

Nicholas J Christopher-Hayes1,2, Sarah C Haynes3, Nicholas J Kenyon4

  • 1Center for Mind and Brain, University of California, Davis.

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Summary
This summary is machine-generated.

Childhood asthma is linked to memory deficits in children. Early-onset asthma may worsen memory impairments and affect executive functions like attention and processing speed.

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Area of Science:

  • Pediatric Health
  • Neuroscience
  • Respiratory Medicine

Background:

  • Asthma is a prevalent chronic respiratory condition in children, affecting millions in the US.
  • While rodent models suggest asthma can cause memory deficits, its impact on children's memory development is not well understood.

Purpose of the Study:

  • To investigate the association between childhood asthma and cognitive abilities, specifically memory, in children.
  • To determine if asthma onset timing influences memory development and executive functions.

Main Methods:

  • A longitudinal cohort study utilizing data from the Adolescent Brain Cognitive Development (ABCD) Study.
  • Included approximately 11,800 children aged 9-10 years, with follow-up over two years.
  • Analyzed associations between parent-reported asthma status (early-onset, late-onset, or no history) and cognitive outcomes, including episodic memory, processing speed, and executive functions.

Main Results:

  • Children with earlier onset of asthma showed slower longitudinal improvements in memory compared to controls.
  • In cross-sectional analysis, children with asthma scored lower on episodic memory, processing speed, and inhibition/attention tasks.
  • These cognitive deficits were observed across multiple domains, including memory and executive functions.

Conclusions:

  • Childhood asthma is associated with impaired memory abilities in children.
  • The severity of memory difficulties may be greater with earlier asthma onset.
  • Asthma may also negatively impact executive functions such as processing speed and attention.