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Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
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Scleroderma Renal Crisis and Musculoskeletal Corticosteroid Injections.

Maheswari Muruganandam1, Eyerusalem B Akpan, Matthew K McElwee

  • 1From the University of New Mexico Health Sciences Center, Albuquerque, NM.

Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases
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Musculoskeletal corticosteroid injections are safe for systemic sclerosis patients, showing no increased risk of scleroderma renal crisis. Careful monitoring is advised for high-risk individuals post-injection.

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Area of Science:

  • Rheumatology
  • Immunology

Background:

  • Inflammatory arthritis is common in systemic sclerosis (SSc).
  • Musculoskeletal corticosteroid (MSKC) injections are often avoided in SSc patients due to concerns about scleroderma renal crisis (SRC).

Purpose of the Study:

  • To investigate the incidence of SRC following MSKC injections in patients with SSc.

Main Methods:

  • A cohort of 136 SSc patients was studied, with 46 receiving a total of 330 MSKC injections of triamcinolone acetonide.
  • Patient data including blood pressure, serum creatinine and glucose, and urine protein were collected before and after injections.
  • Complications were systematically recorded.

Main Results:

  • No significant changes in systolic or diastolic blood pressure, creatinine, glucose, or urine protein-creatinine ratio were observed post-MSKC injection.
  • The incidence of SRC was zero in the MSKC group, compared to one case with mortality in the control group.
  • No infections, hematologic abnormalities, or tendon ruptures were reported in the MSKC group.

Conclusions:

  • MSKC injections appear generally safe in established SSc patients, with a low incidence of SRC and other complications.
  • Monitoring is recommended for high-risk SSc patients and those with recent-onset SSc following MSKC injections.