Related Experiment Video
Updated: Jun 7, 2025

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
[A rare side effect of antithyroid drug therapy]
Armgard Büchel-Boekstegers1,2, Markus Koster3, Sven Lieberherr4
1Kantonsspital Münsterlingen, Medizinische Klinik, Onkologie Spitalcampus 1, 8596 Münsterlingen.
Introduction:
We report a case of Graves' disease in a patient who initially received carbimazole therapy, which was switched to propylthiouracil due to adverse effects. After 14 months of propylthiouracil therapy, the patient developed cutaneous ANCA-associated vasculitis. Prompt cessation of propylthiouracil and topical treatment led to complete resolution of the skin lesions.
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