Fluorescence sensing techniques for quality evaluation of traditional Chinese medicines: a review

Traditional Chinese medicines (TCMs) are highly valued and widely used worldwide. However, their complex compositions and various preparation processes have brought considerable challenges to the quality evaluation of Chinese medicines. The traditional methods for TCM quality evaluation suffer from the problems of cumbersome sample preparation, a long detection time, low sensitivity, etc. A more efficient and accurate evaluation method is urgently needed to ensure the stability and reliability of the quality of TCMs. As an emerging analytical technology, a fluorescent probe has the advantages of high sensitivity, high selectivity, easy operation, etc. It is capable of generating a specific fluorescent signal response to specific components in traditional Chinese medicines, realizing rapid and accurate detection of target components, which effectively solves the many difficulties of traditional methods. The purpose of this paper is to discuss the application of fluorescent probes in the quality evaluation of traditional Chinese medicines and the challenges they face. By introducing the principles, advantages and specific application cases of fluorescent probe technology in the quality evaluation of traditional Chinese medicines, we hope to provide new and efficient analytical ideas for the quality evaluation of traditional Chinese medicines.