[STUDY OF PREVENTION STRATEGIES FOR SIX RISK FACTORS IN REDUCING MORTALITY FROM NON-COMMUNICABLE DISEASES 25 × 25]

Area of Science:

• Public Health
• Epidemiology
• Preventive Medicine

Background:

• Non-communicable diseases (NCDs) show alarming progression, exacerbated by increasing and emerging risk factors, including post-COVID syndrome.
• The atherosclerotic process and cardiovascular diseases are advancing, linked to the influence of six leading risk factors targeted by the «25 × 25» initiative.
• Aggravation of NCDs necessitates a focus on dominant risk factors and effective secondary prevention strategies.

Purpose of the Study:

• To review literature on dominant risk factors contributing to NCD development.
• To explore and justify the early implementation of secondary prevention strategies for NCDs.
• To analyze international experiences in reducing NCDs through risk factor modification.

Main Methods:

• Bibliometric analysis of literature from Scopus, Web of Science, MedLine, The Cochrane Library, and PubMed.
• Literature review focusing on conceptual directions of leading NCD risk factors.
• Analysis of country-specific data on NCD reduction strategies.

Main Results:

• Achieving six risk factor correction goals can significantly decrease morbidity and mortality from major NCDs (cardiovascular diseases, COPD, stomach cancer, diabetes mellitus).
• The «25 × 25» target aims to reduce NCD levels by 2025.
• A 77% reduction in the gap between current trends and target NCD levels is projected through risk factor correction.

Conclusions:

• Early and comprehensive implementation of secondary prevention is crucial for mitigating NCD progression.
• Addressing the six leading risk factors is a viable strategy to approach the «25 × 25» goals for major NCDs.
• International collaboration and data analysis highlight effective methods for NCD control.