Defining clavicle growth in infancy using chest radiographs

Yvonne Hadamek1, Paul-Christian Krueger1, Hans-Joachim Mentzel1

  • 1Section of Pediatric Radiology, Department of Radiology, Jena University Hospital, Jena, Germany.

Frontiers in Pediatrics
|November 13, 2024
PubMed

Insights

This study establishes clavicle growth curves from preterm infants to toddlers up to age 6 using chest X-rays. Findings reveal significant sex and side differences, providing crucial normative data for child development and forensic analysis.

Area of Science:

  • Pediatric Radiology
  • Human Growth and Development
  • Skeletal Biology

Background:

  • Limited research exists on clavicle growth patterns in early childhood, hindering the establishment of normative growth parameters.
  • The clavicle's role in understanding growth and development necessitates detailed investigation during early life stages.

Purpose of the Study:

  • To measure clavicle dimensions and construct growth curves from preterm infants to 6-year-olds using routine chest radiographs.
  • To analyze sex and bilateral differences in clavicle growth.
  • To establish normative clavicle growth parameters for clinical and forensic applications.

Main Methods:

  • Retrospective analysis of chest radiographs from children aged 23 weeks gestation to 6 years (January 2010 - June 2020).
  • Measurement of clavicle length and width using Centricity™ Universal Viewer on 1,340 qualifying radiographs.
  • Statistical analysis performed using SPSS® to identify growth trends and differences.

Main Results:

  • Clavicle length and width demonstrated a consistent increasing trend with age, with a noted decrease when including premature infants in the one-month age group.
  • Statistically significant differences were observed between the left and right clavicles, as well as between sexes.
  • Measurements derived from thoracic radiographs proved highly accurate, supporting their use for clavicle assessment.

Conclusions:

  • Routine chest radiographs are a reliable tool for assessing clavicle growth, offering high accuracy in measurements.
  • The established reference values provide a foundation for normative growth parameters in pediatric populations.
  • This study addresses a critical gap in understanding early childhood clavicle development, with implications for clinical and forensic contexts.
Abstract

Related Concept Videos

Changes in the Appendicular Skeleton with Age01:09

Changes in the Appendicular Skeleton with Age

The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
1.8K
Growth of Cartilage and Bone Tissue01:27

Growth of Cartilage and Bone Tissue

Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
3.1K
Bone Formation by Endochondral Ossification01:24

Bone Formation by Endochondral Ossification

Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
3.9K
The Thoracic Cage: Sternum01:17

The Thoracic Cage: Sternum

The thoracic or rib cage forms the body's thorax (chest) portion. Its primary function in the body is to protect vital organs in the thoracic cavity, such as the heart and the lungs. It consists of 12 pairs of ribs with their costal cartilages and the sternum. The ribs are anchored posteriorly to the 12 thoracic vertebrae (T1-T12).
The sternum is the elongated bony structure on the anterior side of the thoracic cage. It consists of three parts: the manubrium, the body, and the xiphoid...
1.9K
Physical Assessment of the Respiratory Tract II: Inspection01:27

Physical Assessment of the Respiratory Tract II: Inspection

Physical assessment of the respiratory tract through inspection is a crucial step in understanding the patient's respiratory health. It provides insights into the functioning of the respiratory system, the musculoskeletal structure, and even the patient's nutritional status. This comprehensive approach involves observing several vital aspects: chest configuration, breathing patterns, respiratory rates, skin color, and use of accessory muscles.
Chest Configuration
The chest configuration...
233
The Thoracic Cage: Ribs01:20

The Thoracic Cage: Ribs

Ribs are curved, flattened bones forming the thoracic cavity wall with the thoracic muscles. There are 12 pairs of thoracic ribs. The posterior ends of all the ribs articulate with the T1–T12 thoracic vertebrae. In contrast,the anterior ends of most ribs attach to the sternum via their costal cartilages.
Parts of a Typical Rib
A typical rib has a head, neck, and body. The posterior end of the rib is called the head, followed by a narrow neck. The head articulates primarily with the costal...
2.4K