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Defining clavicle growth in infancy using chest radiographs
Yvonne Hadamek1, Paul-Christian Krueger1, Hans-Joachim Mentzel1
1Section of Pediatric Radiology, Department of Radiology, Jena University Hospital, Jena, Germany.
Insights
This study establishes clavicle growth curves from preterm infants to toddlers up to age 6 using chest X-rays. Findings reveal significant sex and side differences, providing crucial normative data for child development and forensic analysis.
Area of Science:
- Pediatric Radiology
- Human Growth and Development
- Skeletal Biology
Background:
- Limited research exists on clavicle growth patterns in early childhood, hindering the establishment of normative growth parameters.
- The clavicle's role in understanding growth and development necessitates detailed investigation during early life stages.
Purpose of the Study:
- To measure clavicle dimensions and construct growth curves from preterm infants to 6-year-olds using routine chest radiographs.
- To analyze sex and bilateral differences in clavicle growth.
- To establish normative clavicle growth parameters for clinical and forensic applications.
Main Methods:
- Retrospective analysis of chest radiographs from children aged 23 weeks gestation to 6 years (January 2010 - June 2020).
- Measurement of clavicle length and width using Centricity™ Universal Viewer on 1,340 qualifying radiographs.
- Statistical analysis performed using SPSS® to identify growth trends and differences.
Main Results:
- Clavicle length and width demonstrated a consistent increasing trend with age, with a noted decrease when including premature infants in the one-month age group.
- Statistically significant differences were observed between the left and right clavicles, as well as between sexes.
- Measurements derived from thoracic radiographs proved highly accurate, supporting their use for clavicle assessment.
Conclusions:
- Routine chest radiographs are a reliable tool for assessing clavicle growth, offering high accuracy in measurements.
- The established reference values provide a foundation for normative growth parameters in pediatric populations.
- This study addresses a critical gap in understanding early childhood clavicle development, with implications for clinical and forensic contexts.
Background:
Despite the critical role of the clavicle in understanding growth and development in early childhood, there remains a notable paucity of comprehensive studies investigating clavicle growth patterns during this crucial period. This hinders our ability to establish normative growth parameters during these early life stages. Our study sought to measure clavicle dimensions and subsequently construct growth curves spanning from preterm infants to toddlers up to the age of 6 years by measuring routine chest radiographs. Differences between both sides of the body and between the sexes should be analysed. This aimed to provide a nuanced understanding of clavicle growth dynamics and offering a foundation for the establishment of normative values in this understudied context. In this retrospective study, children aged 23 weeks of gestation to 6 years who underwent a chest radiography between January 2010 and June 2020 were enrolled. A total of 5.311 potential radiographs was screened. Clavicle length and width were measured in all radiographs using the Centricity™ Universal Viewer. Statistical analysis was performed using SPSS®.
Results:
1.340 images met the quality criteria to be included in our study. The growth curves of clavicle lengths and widths showed a steadily increasing trend with age. Inclusion of premature infants in the age group of one month resulted in a decrease in this age group. Significant differences between both sides of the body and between the sexes could be shown. Measurements of clavicle length and width, derived from routine chest radiographs, are highly accurate. This accuracy underscores the potential for utilizing thoracic radiographs as a reliable tool for assessing clavicle growth in clinical settings or even forensic analysts. The establishment of reference values derived from our measurements provides a basis for normative growth parameters.
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