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Published on: April 5, 2024
Increased antinuclear (anti-Sm) antibodies in infertile patients with peritoneal endometriosis
Renata Fogaça Borges1, Vanessa Krebs Genro2, Carlos Augusto Bastos de Souza2
1Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Objective:
The aim of this study is to evaluate the intensity of five antibodies against extractable nuclear antigens (ENA: RNP, ScL-70, SS-B, SS-A, and Sm) in infertile patients with endometriosis.
Methods:
We investigated infertile women with minimal/mild endometriosis (n=43) and fertile women (n=46).
Results:
The intensity of immunoreactions was also similar for anti-RNP and anti-SS-A antibodies. However, the intensity of immunoreactivity for anti-Sm antibodies was higher in the endometriosis group.
Conclusions:
Patients with minimal/mild endometriosis have higher levels of anti-Sm autoantibodies.
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