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Updated: Jun 7, 2025

Phthalic Acid Ester-Binding DNA Aptamer Selection, Characterization, and Application to an Electrochemical Aptasensor
Published on: March 21, 2018
A high affinity and selective DNA aptamer for copper ions
Jin Wang1,2, Yibo Liu2, Xiangmei Li1
1Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou 510642, China. hongtao@scau.edu.cn.
Abstract:
Capture-SELEX was employed for the selection of DNA aptamers for Cu2+. The best aptamer named Cu-1 has a Kd of 14.2 nM as determined using the strand-displacement assay, representing an approximate 3000-fold improvement over a previously reported Cu2+ aptamer. The sensor achieved a limit of detection of 2.1 nM.
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