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Updated: Jun 7, 2025

A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq
Published on: May 28, 2021
Evolutionary bioinformatics with veiled biological database for health care operations
Hariprasath Manoharan1, S A Edalatpanah2
1Department of Electronics and Communication Engineering, Panimalar Engineering College, Poonamallee-600 123, Tamil Nadu, India.
This study introduces a novel bioinformatics approach for real-time healthcare data processing using medical sensors. The genetic and ant colony optimization (GACO) method significantly reduces errors and enhances service quality in big data analysis.
Area of Science:
- Bioinformatics
- Health Informatics
- Computational Biology
Background:
- The proliferation of biological data processing systems in healthcare necessitates real-time information access.
- Bioinformatics integration into wireless technologies is crucial for capturing physical characteristics.
- Existing systems face challenges in processing large volumes of healthcare data efficiently.
Purpose of the Study:
- To propose an evolutionary bioinformatics model for medical sensor applications in healthcare.
- To optimize data processing using a hybrid genetic and ant colony optimization (GACO) approach.
- To minimize errors and maximize the quality of service (QoS) in real-time big data processing.
Main Methods:
- Implementation of a novel design with dedicated transmitting and receiving modules.
- Framing individual bits for enhanced bioinformatics data processing.
- Combining genetic algorithms (GA) and ant colony optimization (ACO) for system optimization (GACO).
Main Results:
- The proposed design effectively minimizes errors in big data processing stages.
- All channels are accessed according to framed bits, reducing overall data processing errors.
- Maximized quality of service (QoS) achieved by maintaining high-quality bits for bioinformatics data channels.
Conclusions:
- The developed technique successfully handles bioinformatics data for healthcare applications in real-time.
- The GACO optimization method demonstrates significant improvements in error reduction and QoS.
- Achieved a service quality of 95% in experimental evaluations, validating the model's effectiveness.
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