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Published on: November 23, 2013
Anti N-methyl-D-aspartate receptor encephalitis during pregnancy: A case report
Leïa Kennel1, Dominique Luton1, Florence Gressier2
1Université Paris-Saclay, AP-HP, Hôpital Bicêtre, Service de Gynécologie-Obstétrique, 78, avenue du Général Leclerc - 94276 Le Kremlin-Bicêtre, France.
Abstract:
Anti-N-methyl-D-aspartate receptor (NMDA-R) encephalitis is an immune-mediated encephalitis that primarily affects young women. Due to the psychiatric and neurological symptoms, the diagnosis can be challenging, especially during pregnancy. During pregnancy, treatments must take into account the fetal and neonatal risk and the risk of premature delivery. We report a case of anti-NMDA encephalitis in a 31-years-old, 30 weeks pregnant women characterized by predominantly psychiatric symptoms, associated with ovarian teratoma. First-line treatments have led to an improvement in symptoms, allowing the pregnancy to be carried to term and a vaginal delivery.
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