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Clinical Experiences Using CyberKnife for Large-Volume Meningiomas: A Preliminary Study
Yonghun Song1,2, Kyeong-O Go1,3
1Department of Neurosurgery, Gyeongsang National University Changwon Hospital, Changwon, Korea.
Brain Tumor Research and Treatment
|November 14, 2024
Summary
CyberKnife radiosurgery (CKRS) shows promise for large meningiomas, achieving high tumor control and survival rates. While complications like edema occurred, they were generally manageable, suggesting CKRS as a viable treatment option.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Oncology
Background:
- Evaluating CyberKnife radiosurgery (CKRS) for large meningiomas (≥10 cm³).
- Addressing treatment challenges in patients with limited surgical options due to tumor location or health conditions.
Purpose of the Study:
- To assess the safety and efficacy of CKRS in treating large-volume meningiomas.
- To determine tumor control and survival rates following CKRS treatment.
Main Methods:
- Retrospective analysis of 18 patients with meningiomas treated with CKRS.
- Data collected from Gyeongsang National University Hospital between 2010 and 2020.
- Regular follow-up imaging to evaluate tumor control and survival.
Main Results:
- Achieved a 5-year overall survival rate of 92.3%.
- Demonstrated a 5-year tumor control rate of 93.8%.
- Reported symptomatic peritumoral edema in 61.1% of patients, with 16.7% requiring surgery.
Conclusions:
- CKRS is a potentially effective treatment for large meningiomas.
- The procedure offers good tumor control with manageable complications.
- Further research with larger patient groups is recommended to validate these findings.
