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Updated: Jun 7, 2025
Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
Clinical Experiences Using CyberKnife for Large-Volume Meningiomas: A Preliminary Study
Yonghun Song1,2, Kyeong-O Go1,3
1Department of Neurosurgery, Gyeongsang National University Changwon Hospital, Changwon, Korea.
Background:
This preliminary study evaluates the safety and efficacy of CyberKnife radiosurgery (CKRS) for large-volume meningiomas (≥10 cm³), where surgical options may be limited due to tumor location or patient health conditions.
Methods:
We retrospectively analyzed 18 patients with meningiomas treated with CKRS at Gyeongsang National University Hospital between 2010 and 2020. Tumor control and survival rates were evaluated, with follow-up imaging performed regularly.
Results:
CKRS achieved a 5-year overall survival rate of 92.3% and a 5-year tumor control rate of 93.8%. Symptomatic peritumoral edema occurred in 61.1% of patients, with 16.7% requiring surgical intervention.
Conclusion:
CKRS appears to be a promising option for patients with large meningiomas, showing good tumor control and manageable complications. Further studies with larger cohorts are necessary to confirm these findings.
