Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Cancer01:30

Skin Cancer

3.8K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
3.8K
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

2.7K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
2.7K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

3.6K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Risk of Immunologic Reactions During Monthly Therapy for Hansen Disease.

JAMA dermatology·2026
Same author

Skin cancer risk in alopecia areata: a systematic review and meta-analysis.

Frontiers in oncology·2026
Same author

Aryl Hydrocarbon Receptor Expression in Cutaneous Lupus: A Clinicopathologic Correlation.

The American Journal of dermatopathology·2026
Same author

Implementation of low-dose buprenorphine induction at a syringe services program.

Addiction science & clinical practice·2026
Same author

Comparing Diagnostic Accuracy of Shave Versus Punch Biopsies in Cutaneous T-Cell Lymphoma.

The American Journal of dermatopathology·2026
Same author

Prebiotics, Probiotics, and Postbiotics for Acne Vulgaris: A Systematic Review.

Dermatology and therapy·2026
Same journal

The Evidence Is In: Devices and Biologics Reshaping Modern Dermatology.

Dermatologic clinics·2026
Same journal

Energy-Based Devices for Body Contouring.

Dermatologic clinics·2026
Same journal

Microfocused Ultrasound with Visualization for Skin Tightening: Clinical Applications, Safety, and Technical Considerations.

Dermatologic clinics·2026
Same journal

Devices in Onychomycosis: A Status Update.

Dermatologic clinics·2026
Same journal

Acne Laser Devices in Dermatology.

Dermatologic clinics·2026
Same journal

Fractional Laser Therapy for Androgenetic Alopecia: Mechanisms, Clinical Evidence, and Practical Implementation.

Dermatologic clinics·2026
See all related articles

Related Experiment Video

Updated: Jun 7, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:38

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

35

Innovations in Cutaneous Lupus.

Rachel R Lin1, Peyton V Warp1, Mara A Hartoyo1

  • 1Department of Dermatology, University of Miami Miller School of Medicine, 1120 Northwest 14th Street, Suite 9, Miami, FL 33136, USA.

Dermatologic Clinics
|November 14, 2024
PubMed
Summary
This summary is machine-generated.

Cutaneous lupus erythematosus (CLE) management is improving with new systemic medications and biologics. This review covers updated pharmaceuticals and guidelines for better patient outcomes in this chronic skin condition.

Keywords:
Biological therapiesClinical trial overviewConnective tissue diseaseCutaneous lupus erythematosus

More Related Videos

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
12:04

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

Published on: November 1, 2015

17.4K
Granulocyte-dependent Autoantibody-induced Skin Blistering
12:23

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

10.5K

Related Experiment Videos

Last Updated: Jun 7, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:38

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

35
The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
12:04

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

Published on: November 1, 2015

17.4K
Granulocyte-dependent Autoantibody-induced Skin Blistering
12:23

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

10.5K

Area of Science:

  • Dermatology
  • Immunology
  • Rheumatology

Background:

  • Cutaneous lupus erythematosus (CLE) is an autoimmune skin condition.
  • Current treatments offer moderate efficacy, leaving unmet patient needs.
  • Chronic CLE symptoms like pruritus, scarring, and dyspigmentation reduce quality of life.

Purpose of the Study:

  • To provide an updated overview of the clinical management of CLE.
  • To discuss new pharmaceuticals and treatment guidelines for CLE.
  • To highlight advancements in addressing unmet therapeutic needs in CLE patients.

Main Methods:

  • Review of current literature on CLE treatments.
  • Discussion of emerging systemic medications and biologics.
  • Analysis of recent clinical practice guidelines for CLE management.

Main Results:

  • New biologics and systemic agents offer expanded therapeutic options for CLE.
  • Advancements address key symptoms such as pruritus, scarring, and dyspigmentation.
  • Updated guidelines provide a framework for optimizing CLE care.

Conclusions:

  • The therapeutic landscape for CLE has significantly advanced.
  • New treatments improve the management of chronic CLE symptoms and quality of life.
  • Collaboration between dermatologists and rheumatologists is key for effective CLE management.