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Updated: Jun 7, 2025

Bedside Ultrasound for Guiding Fluid Removal in Patients with Pulmonary Edema: The Reverse-FALLS Protocol
Published on: July 28, 2018
A Rare Case of Pulmonary Edema Secondary to Hydrochlorothiazide Use
Evan J Chen1,2, Laurie Hayrapetian1,2, Katherine Frishe1
1Department of Internal Medicine, Los Angeles General Medical Center, Los Angeles, California, USA.
Abstract:
Noncardiogenic pulmonary edema has been reported as a rare adverse reaction of hydrochlorothiazide. Symptoms can develop acutely after medication ingestion, and patients may present acutely ill. The mechanism by which hydrochlorothiazide causes pulmonary edema remains unknown and is considered idiosyncratic. Prompt supportive care and discontinuation of the medication is necessary to prevent and manage such a complication. This case report describes a patient who developed noncardiogenic pulmonary edema after taking a combination pill of hydrochlorothiazide-losartan.
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