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Related Concept Videos

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...

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Related Experiment Video

Updated: Jul 14, 2026

Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer
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Pseudo-Synchronous Colorectal Cancer: A Case Report.

Jose L Mejia1, Luis A Mejia Sierra2

  • 1General Surgery, Ephrata Community Hospital/WellSpan Health, Ephrata, USA.

Cureus
|November 15, 2024
PubMed
Summary

This case report details a rare instance of metastatic cecal cancer to the rectum, termed "pseudo-synchronous" due to its unique presentation. This finding challenges existing understanding of colorectal cancer metastasis patterns.

Keywords:
colon cancermetastatic colon cancermucinous colon cancerright colon cancersynchronous colon cancer

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Area of Science:

  • Oncology
  • Gastroenterology

Background:

  • Colorectal cancer is a prevalent malignancy with varying metastatic patterns based on tumor location and histology.
  • Sporadic colorectal cancer, a somatic genetic disease, is influenced by both the colonic environment and host genetics.
  • Synchronous colorectal cancers are diagnosed concurrently or within six months post-operation.

Observation:

  • A patient presented with colon cancer and obstructive symptoms, revealing a primary lesion in the cecum.
  • A secondary lesion was identified in the rectum, below normal mucosa, distinct from the primary cecal tumor.
  • This metastatic pattern from cecum to rectum is unprecedented in current medical literature.

Findings:

  • The rectal lesion, found below normal mucosa, was classified as metastatic from the primary cecal cancer.
  • The term "pseudo-synchronous" was adopted to describe this rare metastatic presentation.
  • This case highlights an unusual metastatic pathway for colorectal cancer.

Implications:

  • This case expands the understanding of colorectal cancer's metastatic potential and behavior.
  • Further research is warranted to elucidate the mechanisms behind this rare metastatic pattern.
  • Clinical vigilance for unusual metastatic sites in colorectal cancer is crucial.