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Pediatric Post-Intensive Care Syndrome and Current Therapeutic Options

Cydni N Williams1, Neethi P Pinto2, Gillian A Colville3

  • 1Division of Pediatric Critical Care, Department of Pediatrics, Pediatric Critical Care and Neurotrauma Recovery Program, 707 SW Gaines Street, CDRC-P, Portland, OR 97239, USA.

Critical Care Clinics
|November 15, 2024
PubMed

Insights

Post-intensive care syndrome (PICS) affects most pediatric critical care survivors across multiple health domains. Addressing unique challenges in children requires specialized approaches and multidisciplinary clinics for effective intervention.

Area of Science:

  • Pediatric critical care medicine
  • Pediatric survivorship research
  • Neurodevelopmental disorders

Background:

  • Post-intensive care syndrome (PICS) is a prevalent condition affecting survivors of critical care.
  • PICS encompasses physical, cognitive, emotional, and social health impairments.
  • Pediatric PICS presents unique challenges due to age-related biological differences, disease variability, and environmental factors.

Purpose of the Study:

  • To highlight the multifaceted nature of PICS in pediatric survivors.
  • To underscore the specific challenges in diagnosing and managing PICS in children.
  • To emphasize the growing recognition and opportunities for intervention in pediatric PICS.

Main Methods:

  • Review of emerging literature on pediatric critical care survivorship.
  • Analysis of the heterogeneity in pediatric populations and neurodevelopmental stages.
  • Examination of the lack of standardized measurements for pediatric PICS morbidities.

Main Results:

  • PICS impacts physical, cognitive, emotional, and social health in pediatric survivors.
  • Pediatric PICS diagnosis and treatment are complicated by age, disease, environment, and measurement issues.
  • Specialized multidisciplinary clinics are emerging to address pediatric PICS.

Conclusions:

  • Pediatric PICS is a significant concern requiring tailored interventions.
  • Multidisciplinary approaches are crucial for managing PICS in pediatric survivorship.
  • Further research and standardized tools are needed to improve pediatric PICS outcomes.

Keywords:
Cognitive functionCritical careOutcomesParentsPediatricsRehabilitation

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