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Updated: May 7, 2026

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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
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Rathke's cleft cyst apoplexy presented as pituitary apoplexy: A case report
Soumya Pahari1, Yugant Khand2, Stuti Yadav1
1Shree Birendra Hospital, Chhauni, Kathmandu 44600, Nepal.
International Journal of Surgery Case Reports
|November 16, 2024
Summary
Rathke's cleft cysts (RCC) rarely present with hemorrhage, mimicking pituitary apoplexy. Surgical evacuation offers a promising outcome for these non-malignant pituitary lesions.
Area of Science:
- Neurosurgery
- Endocrinology
- Pathology
Background:
- Rathke's cleft cysts (RCC) are benign pituitary gland lesions.
- Pituitary apoplexy is typically associated with macroadenomas, not RCCs.
Observation:
- A 30-year-old male presented with headache and vomiting due to a hemorrhagic RCC.
- Endonasal transsphenoidal surgery successfully evacuated the cyst.
- Histology confirmed the diagnosis of RCC.
Findings:
- Hemorrhage in RCCs can mimic pituitary tumor apoplexy, complicating diagnosis.
- Surgical management is effective for hemorrhagic RCCs.
- Long-term hormonal replacement may be necessary post-surgery.
Implications:
- Considering RCC in the differential diagnosis of pituitary lesions with hemorrhage is crucial.
- Surgical intervention yields favorable outcomes for hemorrhagic RCC.
- This case highlights the importance of accurate diagnosis and management of rare pituitary pathologies.
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