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Sequence signals in eukaryotic upstream regions.

R Nussinov, J Owens, J V Maizel

Biochimica Et Biophysica Acta

|March 26, 1986

Summary

Transcription factors bind to promoter elements like TATAAATA and CCAAT to regulate gene expression. This study reveals a strong upstream TAT/ATA signal at -275, suggesting a more complex regulatory mechanism than previously understood.

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