Related Experiment Video
Updated: Jun 7, 2025

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy
Published on: July 3, 2014
Cardiac Complications of Radiation Therapy
Raja Zaghlol1, Lauren Pedersen2, Syed Qamer1
1Division of Cardiovascular Disease, Cardio-oncology Section, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8086, St Louis, MO 63110, USA.
Radiation therapy can harm the heart, causing radiation-induced cardiotoxicity (RICT) in cancer survivors. This review covers RICT
Area of Science:
- Cardiology
- Oncology
- Radiation Oncology
Background:
- Radiation therapy is vital for cancer treatment, improving survival rates.
- Thoracic radiation can cause unintended injury to the heart, leading to radiation-induced cardiotoxicity (RICT).
- With increased cancer survival, RICT is a growing concern.
Purpose of the Study:
- To review the spectrum and pathophysiology of radiation-induced cardiotoxicity (RICT).
- To summarize current recommendations for RICT risk stratification, screening, prevention, and management.
- To briefly discuss novel uses of radiation in cardiac conditions.
Main Methods:
- Literature review of radiation-induced cardiotoxicity.
- Synthesis of contemporary guidelines for RICT management.
- Exploration of emerging applications of radiation therapy.
Main Results:
- Radiation-induced cardiotoxicity (RICT) presents a spectrum of cardiac issues.
- Established protocols exist for managing RICT.
- Radiation therapy is being explored for treating cardiac arrhythmias.
Conclusions:
- Radiation-induced cardiotoxicity (RICT) is an important clinical consideration in cancer survivors.
- Comprehensive strategies are available for RICT prevention and management.
- Radiation therapy holds potential for novel cardiac applications.
Related Concept Videos
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Rheumatic Heart Disease I: Introduction
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
Pericarditis IV: Nursing Management

