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Updated: Jun 7, 2025

Light-driven Enzymatic Decarboxylation
Published on: May 22, 2016
Photoinduced Single Electron Transfer via EDA Complexation Enables Decarbonylative C(sp2)-S Bond Formation
Swagata Choudhury1, Sudipta Raha Roy1
1Department of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India.
Abstract:
We have developed a photoinduced transition-metal-free decarbonylative strategy at ambient temperature through non-covalent interactions to achieve vinyl sulfones. Traditionally, decarbonylative functionalization is accomplished using transition metal catalysts at elevated temperatures. The π-π interaction facilitates the elimination of CO to generate vinyl radical, thereby promoting the creation of C-S bonds with the sulfonyl radical. These interactions and the overall process were illuminated by spectroscopic investigations and mechanistic studies.
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