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Overview of Regeneration and Repair

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Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
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Updated: Jun 7, 2025

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling

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Nanoscale Generators for Tissue Healing: A Perspective.

Subhasmita Swain¹, R D K Misra², Tapash R Rautray¹

¹Biomaterials and Tissue Regeneration Laboratory, Centre of Excellence, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India.

International Journal of Nanomedicine

|November 20, 2024

Summary

This summary is machine-generated.

Self-powered nanogenerators offer biocompatible solutions for tissue healing and neuronal control. This review explores piezoelectric and triboelectric materials for advanced biomedical applications like bone regeneration and tissue engineering.

Keywords:

nanogenerator piezoelectric tissue engineering triboelectric

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Area of Science:

Biomedical Engineering
Materials Science
Nanotechnology

Background:

Electroactive components are crucial for tissue healing and neuronal activity regulation.
The demand for portable electronics necessitates efficient, miniaturized power sources.
Nanogenerators offer a sustainable solution by harvesting ambient energy.

Purpose of the Study:

To review the development of nanogenerators for biomedical applications.
To focus on piezoelectric and triboelectric materials for tissue engineering.
To discuss future scope and challenges in nanogenerator technology.

Main Methods:

Review of existing literature on nanogenerators in biomedicine.
Focus on piezoelectric and triboelectric materials.
Analysis of applications in tissue regeneration and microbial sterilization.

Main Results:

Nanogenerators provide flexible, transportable, and cost-effective energy solutions.
Piezoelectric and triboelectric materials show promise for bone regeneration and tissue engineering.
These materials facilitate osteogenic proliferation, differentiation, and microbial sterilization.

Conclusions:

Self-powered nanogenerators are essential for long-term functioning of implanted biomedical devices.
Nanogenerators represent a novel area for biomedical investigation with significant potential.
Further research is needed to address challenges and explore future applications.