Stannous Fluoride Toothpaste Stabilized With Nitrate and Phosphates (SNaP) Reduces Oral Malodor: A Randomized...

Area of Science:

• Oral Health
• Microbiology
• Clinical Dentistry

Background:

• Oral malodor negatively impacts quality of life and can originate from oral bacteria.
• Dentifrices are effective vehicles for delivering therapeutic agents to maintain oral hygiene.
• Consumer preference is key for consistent oral hygiene routines.

Purpose of the Study:

• To identify a consumer-preferred flavor for a new stannous fluoride toothpaste stabilized with nitrate and phosphates (SNaP).
• To clinically evaluate the efficacy of the SNaP toothpaste in reducing oral malodor.

Main Methods:

• Consumer flavor preference testing was conducted via an online questionnaire.
• A 3-week randomized, double-blind clinical study compared SNaP to a negative control (0.76% sodium monofluorophosphate).
• Oral malodor reduction was assessed using the organoleptic method.

Main Results:

• The SNaP toothpaste with a new flavor formulation was selected based on consumer testing.
• After 3 weeks, the SNaP group showed a 32.7% reduction in malodor scores 12 hours post-brushing (P < .001).
• The SNaP group achieved a statistically significant 25.7% greater malodor reduction compared to the control group (P < .001).

Conclusions:

• SNaP toothpaste demonstrates superior efficacy in reducing oral malodor for up to 12 hours post-brushing.
• Stannous fluoride, delivered via toothpaste, offers multiple oral health benefits, including bad breath reduction.