Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

2.9K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor...
2.9K
Vision01:24

Vision

52.9K
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
52.9K
Somatosensory, Motor, and Association Cortex01:24

Somatosensory, Motor, and Association Cortex

413
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
413
Auditory Pathway01:15

Auditory Pathway

4.8K
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
4.8K
Association Areas of the Cortex01:21

Association Areas of the Cortex

5.1K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
5.1K
Overview of Somatic Sensory Pathways01:29

Overview of Somatic Sensory Pathways

4.2K
Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
4.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anterior and posterior retrosplenial cortex form distinct visuospatial circuits in the mouse.

Nature communications·2026
Same author

Dendritic architecture enables de novo computation of salient motion in the superior colliculus.

Current biology : CB·2025
Same author

Behavioral modulations can alter the visual tuning of neurons in the mouse thalamocortical pathway.

Cell reports·2024
Same author

SYNGAP1 deficiency disrupts synaptic neoteny in xenotransplanted human cortical neurons in vivo.

Neuron·2024
Same author

Studying human neural function in vivo at the cellular level: Chasing chimeras?

Cell·2022
Same author

Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer's disease.

Cell reports·2022
Same journal

Increased rates of hybridization in swordtails are associated with water pollution.

Current biology : CB·2026
Same journal

Visual uncertainty and task demands shape active sensing strategies in mice.

Current biology : CB·2026
Same journal

An adaptable, self-organizing, single-cell morphology circuit optimizes suctorian predatory trap structure.

Current biology : CB·2026
Same journal

Temporal tuning of switch-like virulence expression resolves environmental uncertainty through phenotypic heterogeneity.

Current biology : CB·2026
Same journal

An abstract relational map emerges in the human medial prefrontal cortex with consolidation.

Current biology : CB·2026
Same journal

Phloem evolved gradually and asynchronously to xylem in early vascular plants.

Current biology : CB·2026
See all related articles

Related Experiment Video

Updated: Jun 7, 2025

Using Looming Visual Stimuli to Evaluate Mouse Vision
05:07

Using Looming Visual Stimuli to Evaluate Mouse Vision

Published on: June 13, 2019

11.2K

Higher-order cortical and thalamic pathways shape visual processing streams in the mouse cortex.

Xu Han1, Vincent Bonin1

  • 1Neuro-Electronics Research Flanders, 3000 Leuven, Belgium; KU Leuven, Department of Biology & Leuven Brain Institute, 3000 Leuven, Belgium; VIB, 3000 Leuven, Belgium.

Current Biology : CB
|November 20, 2024
PubMed
Summary
This summary is machine-generated.

Neural circuits in higher-order visual areas (HVAs) are shaped by specific inputs from the primary visual cortex (V1) and thalamus. This organization enables specialized visual processing and information flow within the brain.

Keywords:
broadcast modehigher-order visual pathwayintracortical connectivitysublaminar specificitytarget specificitythalamocortical pathwayvisual streams

More Related Videos

Modification of a Colliculo-thalamocortical Mouse Brain Slice, Incorporating 3-D printing of Chamber Components and Multi-scale Optical Imaging
06:05

Modification of a Colliculo-thalamocortical Mouse Brain Slice, Incorporating 3-D printing of Chamber Components and Multi-scale Optical Imaging

Published on: September 18, 2015

8.3K
Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex
08:42

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex

Published on: February 8, 2020

9.9K

Related Experiment Videos

Last Updated: Jun 7, 2025

Using Looming Visual Stimuli to Evaluate Mouse Vision
05:07

Using Looming Visual Stimuli to Evaluate Mouse Vision

Published on: June 13, 2019

11.2K
Modification of a Colliculo-thalamocortical Mouse Brain Slice, Incorporating 3-D printing of Chamber Components and Multi-scale Optical Imaging
06:05

Modification of a Colliculo-thalamocortical Mouse Brain Slice, Incorporating 3-D printing of Chamber Components and Multi-scale Optical Imaging

Published on: September 18, 2015

8.3K
Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex
08:42

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex

Published on: February 8, 2020

9.9K

Area of Science:

  • Neuroscience
  • Visual Processing
  • Neural Circuits

Background:

  • Mammalian vision involves complex processing across interconnected brain regions.
  • Higher-order visual areas (HVAs) process visual features through specialized streams, integrating various inputs.
  • The exact circuit organization underlying HVA specialization is not fully understood.

Purpose of the Study:

  • To investigate the cellular architecture of primary visual cortex (V1) and higher-order visual pathways in mice.
  • To elucidate the roles of these circuits in shaping visual representations within HVAs.

Main Methods:

  • Utilized in vivo functional imaging to observe neural activity.
  • Employed neural circuit tracing techniques to map connections.
  • Analyzed cellular architecture and projection specificity in different cortical layers.

Main Results:

  • HVAs receive preferential inputs from V1 and higher-order pathways with similar spatiotemporal tuning.
  • Layer 2/3 neurons in HVAs show strong selectivity and target-specific projections, indicating cell-type-specific information flow.
  • Layer 5 pathways in HVAs broadcast visual signals broadly, likely for output distribution.
  • Thalamocortical pathways from the lateral posterior nucleus (LP) provide highly specific, non-overlapping inputs to HVAs.

Conclusions:

  • The convergence of laminar, cell-type-specific, intracortical, and thalamocortical pathways is crucial for HVA functional specialization.
  • Specific input organization shapes the diversity of visual information processing in HVAs.
  • Distinct pathways contribute to both specialized processing and broad signal distribution within the visual system.