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Updated: Jun 6, 2025

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Measurement Practice of Slow Gait Speed for Motoric Cognitive Risk Syndrome: A Systematic Review.

Lina Wang1, Liming Su2, Lulu Shi1

  • 1School of Medicine, Huzhou Key Laboratory of Precise Prevention and Control of Major Chronic Diseases, Huzhou University, Huzhou, Zhejiang, China.

Journal of the American Medical Directors Association
|November 21, 2024
PubMed
Summary

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Slow gait speed measurement for motoric cognitive risk (MCR) syndrome diagnosis lacks standardization. This systematic review identified heterogeneity in methods, suggesting a need for a comprehensive procedure to improve diagnostic accuracy for MCR.

Area of Science:

  • Neurology
  • Gerontology
  • Clinical Diagnostics

Background:

  • Motoric Cognitive Risk (MCR) syndrome is a significant predictor of dementia.
  • Accurate measurement of slow gait speed is critical for MCR diagnosis.
  • Existing MCR diagnostic protocols exhibit variability in gait speed assessment.

Purpose of the Study:

  • To systematically review and synthesize slow gait speed measurement practices in MCR diagnosis.
  • To identify critical constructs for a standardized gait speed measurement procedure.

Main Methods:

  • Systematic literature review of studies detailing MCR diagnosis and gait speed measurement.
  • Searched multiple databases (PubMed, Medline, Embase, etc.) until January 2024.
  • Evaluated study quality using JBI Critical Appraisal Checklists and synthesized findings narratively.
Keywords:
Motoric cognitive risk syndromemeasurementslow gait speedsystematic review

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Main Results:

  • 50 studies with 55 cohorts were included, revealing significant heterogeneity in measurement tools, protocols, and cutoff values.
  • Common practices included manual stopwatches, a 4-meter walk with 2-meter buffers, and usual pace walking.
  • Analysis highlighted the need for cohort-specific cutoff values for slow gait speed.

Conclusions:

  • Current slow gait speed measurement in MCR diagnosis is heterogeneous.
  • A proposed 7-construct gait speed measurement procedure could enhance MCR diagnostic accuracy and consistency.
  • Further validation of the proposed procedure is required.