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Adult Myopia Progression
Noel A Brennan1, Xu Cheng1, Mark A Bullimore2
1Johnson & Johnson, Jacksonville, Florida, United States.
Investigative Ophthalmology & Visual Science
|November 22, 2024
Summary
Adults experience significant myopia progression between ages 20 and 50, averaging around -1 diopter. This finding highlights the need for interventions to slow adult myopia and manage future visual impairment risks.
Area of Science:
- Ophthalmology
- Optometry
- Public Health
Background:
- Myopic shift typically occurs during childhood and adolescence.
- Adult-onset myopia and progression in adulthood are less understood.
- Understanding refractive error changes in adulthood is crucial for vision care.
Purpose of the Study:
- To investigate the extent of myopic shift in individuals between 20 and 50 years of age.
- To analyze long-term refractive progression data in adult populations.
- To provide evidence for potential interventions targeting adult myopia.
Main Methods:
- Analysis of three distinct datasets: US population-based prevalence data, German clinical data, and Japanese clinical data.
- Utilized logit transformation of prevalence data for US population estimates.
- Extracted, adjusted, and analyzed clinical progression data across different age bands and refractive error groups.
Main Results:
- All three studies indicated an average myopia progression of approximately -1 diopter (D) between ages 20 and 50.
- Progression rates varied based on baseline refractive error, generally increasing with higher myopia.
- Progression was most pronounced between ages 20 and 30, with rates declining with increasing age.
Conclusions:
- Evidence suggests significant myopia progression occurs during adulthood (20-50 years).
- Findings have implications for developing strategies to slow adult myopia progression.
- Understanding adult progression aids in projecting future visual impairment related to myopia.
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