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Updated: Jun 6, 2025

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Adult Myopia Progression.

Noel A Brennan1, Xu Cheng1, Mark A Bullimore2

  • 1Johnson & Johnson, Jacksonville, Florida, United States.

Investigative Ophthalmology & Visual Science
|November 22, 2024
PubMed
Summary
This summary is machine-generated.

Adults experience significant myopia progression between ages 20 and 50, averaging around -1 diopter. This finding highlights the need for interventions to slow adult myopia and manage future visual impairment risks.

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Area of Science:

  • Ophthalmology
  • Optometry
  • Public Health

Background:

  • Myopic shift typically occurs during childhood and adolescence.
  • Adult-onset myopia and progression in adulthood are less understood.
  • Understanding refractive error changes in adulthood is crucial for vision care.

Purpose of the Study:

  • To investigate the extent of myopic shift in individuals between 20 and 50 years of age.
  • To analyze long-term refractive progression data in adult populations.
  • To provide evidence for potential interventions targeting adult myopia.

Main Methods:

  • Analysis of three distinct datasets: US population-based prevalence data, German clinical data, and Japanese clinical data.
  • Utilized logit transformation of prevalence data for US population estimates.
  • Extracted, adjusted, and analyzed clinical progression data across different age bands and refractive error groups.

Main Results:

  • All three studies indicated an average myopia progression of approximately -1 diopter (D) between ages 20 and 50.
  • Progression rates varied based on baseline refractive error, generally increasing with higher myopia.
  • Progression was most pronounced between ages 20 and 30, with rates declining with increasing age.

Conclusions:

  • Evidence suggests significant myopia progression occurs during adulthood (20-50 years).
  • Findings have implications for developing strategies to slow adult myopia progression.
  • Understanding adult progression aids in projecting future visual impairment related to myopia.