Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Risk of raised posterior corneal elevation associated with cornea and sublayer thicknesses 5 years post keratorefractive lenticule extraction.

BMJ open ophthalmology·2026
Same author

Safety thresholds for removing and preserving corneal tissue in small-incision lenticule extraction: A PRISMA-Compliant study.

Advances in ophthalmology practice and research·2026
Same author

Linking layered corneal compactness to macroscopic biomechanics: <i>in vivo</i> assessment via integrated densitometry and dynamic deformation analysis.

Frontiers in bioengineering and biotechnology·2026
Same author

Development and validation of a risk prediction model for dry eye disease in myopic children.

Frontiers in medicine·2026
Same author

The Wear Resistance of Reinforced Coatings Fabricated by Three Different Processes on High-Density Tungsten Alloy.

Materials (Basel, Switzerland)·2026
Same author

Comparative analysis of epithelial remodeling after photorefractive keratectomy and keratorefractive lenticule extraction for myopia.

Indian journal of ophthalmology·2026
Same journal

Avacincaptad Pegol Slows Progressive Ellipsoid Zone Degradation/Loss in Eyes With Geographic Atrophy.

Ophthalmology·2026
Same journal

Access to Intravitreal Anti-VEGF Drugs in Persons with Medicare Advantage Compared with Medicare Fee-For-Service.

Ophthalmology·2026
Same journal

Re: Dones et al.: Emergency department use of ocular point-of-care ultrasound and its utility in diagnosis at a tertiary academic medical center (Ophthalmology. 2026;133:720-727).

Ophthalmology·2026
Same journal

Cataract Surgery and the Risk of Conversion from Dry to Neovascular Age-related Macular Degeneration in the IRIS© Registry.

Ophthalmology·2026
Same journal

Blunt Ocular Trauma from BB Gun Pellet: Long-Term Corneal Endothelial Changes.

Ophthalmology·2026
Same journal

Atypical Sebaceous Adenoma of the Caruncle.

Ophthalmology·2026
See all related articles

Related Experiment Video

Updated: Jun 6, 2025

Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation
04:59

Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation

Published on: July 7, 2023

2.2K

Evidence-Based Guidelines for Keratorefractive Lenticule Extraction Surgery.

Yan Wang1, Lixin Xie2, Ke Yao3

  • 1Tianjin Eye Hospital, Tianjin Eye Institute, Tianjin Key Laboratory of Ophthalmology and Visual Science, Nankai University Affiliated Eye Hospital, Tianjin, China; Nankai University Eye Institute, Nankai University, Tianjin, China; Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, China.

Ophthalmology
|November 22, 2024
PubMed
Summary
This summary is machine-generated.

New guidelines offer evidence-based recommendations for keratorefractive lenticule extraction (KLEx) procedures. These guidelines aim to improve patient outcomes and minimize complications in refractive surgery.

Keywords:
ComplicationCorneal biomechanicsKeratorefractive lenticule extractionRefractive surgerySmall-incision lenticule extraction

More Related Videos

An &#8220;All-laser&#8221; Endothelial Transplant
09:59

An “All-laser” Endothelial Transplant

Published on: July 6, 2015

9.5K
Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
07:51

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts

Published on: October 21, 2022

1.6K

Related Experiment Videos

Last Updated: Jun 6, 2025

Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation
04:59

Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation

Published on: July 7, 2023

2.2K
An &#8220;All-laser&#8221; Endothelial Transplant
09:59

An “All-laser” Endothelial Transplant

Published on: July 6, 2015

9.5K
Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
07:51

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts

Published on: October 21, 2022

1.6K

Area of Science:

  • Ophthalmology
  • Refractive Surgery
  • Corneal Surgery

Background:

  • Keratorefractive lenticule extraction (KLEx) involves removing corneal tissue via small incisions, avoiding flaps.
  • KLEx has rapidly gained popularity for refractive correction.
  • No established clinical practice guidelines previously existed for KLEx.

Purpose of the Study:

  • To develop evidence-based clinical practice guidelines for keratorefractive lenticule extraction (KLEx).

Main Methods:

  • Guidelines developed using WHO methodology, AGREE II, and PRIME statement.
  • Evidence synthesized from 8 literature databases and 5 guideline databases.
  • Recommendations formulated via Delphi consensus of 44 global experts.

Main Results:

  • 38 recommendations developed for KLEx, covering screening, planning, surgery, and complications.
  • 29 (76%) recommendations were strong, focusing on effective refractive correction and complication management.
  • Corneal biomechanics and research gaps for enhancing safety were identified.

Conclusions:

  • Evidence-based guidelines for KLEx are now available for clinical practice.
  • Guidelines address preoperative screening, surgical planning, and complication management.
  • Implementation is expected to minimize complications and enhance outcomes in refractive surgery.