Related Experiment Video
Updated: Jun 6, 2025

Making, Testing, and Using Potassium Ion Selective Microelectrodes in Tissue Slices of Adult Brain
Published on: May 7, 2018
Potassium Homeostasis
Niraj B Desai1, Melanie P Hoenig2
1Division of Nephrology and Hypertension, Case Western Reserve University School of Medicine, Cleveland, OH.
None:
Potassium homeostasis is essential for maintaining the normal resting membrane potential of excitable cells. Yet daily dietary potassium typically far exceeds total extracellular potassium, thus the body has elegant strategies to shift potassium into cells promptly after a meal and then the kidneys efficiently excrete potassium. Potassium excretion depends on adequate kidney perfusion and filtration, sodium delivery to the distal nephron and aldosterone action on the distal nephron. Both hypokalemia and hyperkalemia have been associated with an increase in mortality. In this piece, we share 5 challenging cases to explore normal potassium homeostasis and disorders that can lead to derangements in potassium balance or excretion.
More Related Videos
08:11Voltage-Dependent Potassium Current Recording on H9c2 Cardiomyocytes via the Whole-Cell Patch-Clamp Technique
Published on: November 11, 2022
12:48Measuring Cation Transport by Na,K- and H,K-ATPase in Xenopus Oocytes by Atomic Absorption Spectrophotometry: An Alternative to Radioisotope Assays
Published on: February 19, 2013
Related Concept Videos
Regulation of Sodium and Potassium
Sodium Regulation
Sodium ions make up approximately 90% of extracellular cations, with a normal blood plasma concentration of 136–148 mEq/L. A decrease in blood volume and pressure triggers the release of renin from granular cells in the juxtaglomerular complex (JGC), primarily...
Roles of Electrolytes: Sodium and Potassium
Antihypertensive Drugs: Potassium-Sparing Diuretics
Resting Potential Decay
At rest, the K+ is the main ion that moves across the membrane...
pH Homeostasis
Respiratory...
Skeleton and Calcium Homeostasis