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Updated: Jun 6, 2025

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Chronic Kidney Disease-Part 1: Evaluation & Risk Assessment in CKD, Methods to Delay CKD Progression
Dana Larsen1, Laalasa Varanasi2, Michelle M Estrella3
1Division of Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, CA; Renal Section, Medical Service, San Francisco VA Health Care System, San Francisco, CA.
Insights
Chronic kidney disease (CKD) is a common condition that increases the risk of death. Early diagnosis and treatment can slow its progression and prevent related heart issues.
Area of Science:
- Nephrology
- Internal Medicine
- Public Health
Background:
- Chronic kidney disease (CKD) is a prevalent condition associated with substantial morbidity and mortality.
- CKD progression contributes to adverse cardiovascular outcomes.
- Timely interventions are crucial for managing CKD and its complications.
Purpose of the Study:
- To provide a case-based overview of critical aspects in CKD diagnosis.
- To outline current approaches for staging CKD.
- To review effective therapeutic strategies for CKD management.
Main Methods:
- Literature review focusing on case studies.
- Synthesis of evidence on diagnostic criteria for CKD.
- Analysis of staging systems and treatment guidelines.
Main Results:
- Case-based examples illustrate diagnostic challenges in CKD.
- Staging is essential for risk stratification and guiding therapy.
- Multifaceted management strategies are key to slowing CKD progression.
Conclusions:
- Early and accurate diagnosis of CKD is paramount.
- Appropriate staging informs personalized treatment plans.
- Effective management can mitigate CKD-related complications and improve patient outcomes.
Abstract:
Chronic kidney disease (CKD) is common and leads to significant morbidity and mortality. Early detection and deployment of effective therapies could prevent CKD progression and related cardiovascular diseases. This review provides a case-based overview of key issues surrounding the diagnosis, staging, and management of CKD.
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