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Related Concept Videos

Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

4
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
4
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

3
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
3

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Transcatheter Tricuspid Valve Replacement Reduces Heart Failure Hospitalization: Insights From the Canadian Evoque Registry.

The Canadian journal of cardiology·2026
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Tricuspid Transcatheter-Edge-to-Edge-Repair and Transcatheter Tricuspid Valve Replacement for Tricuspid Regurgitation: Patient Profiles and Outcomes.

CJC open·2026
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Impact of TAVR Failure Mechanism on Outcomes After Reintervention: From the EXPLANTORREDO-TAVR Registry.

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Automated Referral Prompts Reveal Lack of Equitable Access to Care in Patients With Aortic Stenosis.

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Incidence, Clinical Implications, and Predictors of Paravalvular Leak Following Transcatheter Tricuspid Valve Replacement: The TRIPLACE Registry.

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Related Experiment Video

Updated: Jun 6, 2025

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
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Transcatheter Tricuspid Valve Replacement.

Jörg Hausleiter1, Lukas Stolz2, Philipp Lurz3

  • 1Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.

Journal of the American College of Cardiology
|November 24, 2024
PubMed
Summary

Transcatheter tricuspid valve replacement (TTVR) offers a new treatment for severe tricuspid regurgitation. This review details TTVR

Keywords:
echocardiographyemerging technologies and innovations

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Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiac Surgery

Background:

  • Severe tricuspid regurgitation (TR) poses significant challenges, particularly with complex valve morphology.
  • Transcatheter tricuspid valve replacement (TTVR) is an emerging therapeutic option for high-risk surgical patients.
  • Current treatment strategies for severe TR often involve high surgical risk.

Purpose of the Study:

  • To provide a comprehensive consensus on orthotopic TTVR.
  • To outline patient selection criteria, procedural techniques, and follow-up protocols for TTVR.
  • To serve as a reference for clinicians and researchers in the evolving field of TTVR.

Main Methods:

  • Review of current literature and clinical outcomes from initial TTVR studies and compassionate use cases.
  • Analysis of data focusing on TTVR effectiveness, safety, and patient quality of life.
  • Expert recommendations for periprocedural management, anticoagulation, and long-term follow-up.

Main Results:

  • TTVR demonstrates effectiveness in reducing tricuspid regurgitation.
  • The procedure promotes reverse right ventricular remodeling.
  • Patients undergoing TTVR experience enhanced quality of life.

Conclusions:

  • TTVR is a promising intervention for severe tricuspid regurgitation, especially in complex cases.
  • Potential complications include conduction disturbances, bleeding, and afterload mismatch.
  • Standardized management and follow-up are crucial for successful TTVR outcomes.