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Orthotopic Hind Limb Transplantation in the Mouse
Published on: February 12, 2016
The Decision for Amputation Versus Limb Salvage in Patients with Limb-threatening Lower Extremity Indications: An
Amy L Xu1, Divya Jain2, Casey J Humbyrd2
1Department of Orthopaedic Surgery, The Hospital for Special Surgery, 535 E 70th Street, New York, NY 10021, USA.
Abstract:
Ethical decision-making in the amputation versus limb salvage context requires consideration of respect for patient autonomy, beneficence, and nonmaleficence. The surgical options demonstrate near equivalent outcomes for traumatic indications, while reconstruction is generally favored for threatened limbs due to diabetic complications. The decision for amputation versus limb salvage must be considered in each individual patient's situation, with a shared decision-making process of paramount importance. Discussion should involve the best, worst, and most likely case for each surgical option to allow the patient to better understand the range of potential postoperative courses and make an informed decision.
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