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Fibromuscular Dysplasia: A Focused Review for the Cardiologist
Taylor Petropoulos1,2, Anita Shah3, Andrew Dueck4
1Division of Cardiology, Schulich Heart Program, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Spontaneous coronary artery dissection (SCAD) is linked to fibromuscular dysplasia (FMD). Screening all SCAD patients for FMD is recommended, with a focus on diagnosis and management strategies.
Area of Science:
- Cardiology
- Vascular Medicine
- Radiology
Background:
- Spontaneous coronary artery dissection (SCAD) is a growing cause of acute coronary syndromes.
- Fibromuscular dysplasia (FMD) is a nonatherosclerotic arterial disease causing dissections, stenosis, and aneurysms.
- Extracoronary FMD is found in about 70% of SCAD patients.
Purpose of the Study:
- To review current diagnostic and management approaches for patients with FMD.
- To emphasize the importance of FMD screening in SCAD patients.
Main Methods:
- Literature review of SCAD and FMD diagnosis and management.
- Highlighting computed tomography angiography (CTA) for FMD screening.
Main Results:
- Extracoronary FMD is prevalent in SCAD patients (approx. 70%).
- Lifetime screening for FMD in SCAD patients is advised.
Conclusions:
- Cardiologists should be aware of the FMD-SCAD connection.
- Comprehensive screening and management of FMD are crucial for SCAD patients.
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