Family Genetic-Risk Profiles Associated With Divorce
Jessica E Salvatore1, Henrik Ohlsson2, Jan Sundquist2
1Department of Psychiatry, Robert Wood Johnson Medical School, Rutgers University.
Abstract:
We used Swedish national register data (N = 2,828,777) to examine divorce and its associated patterns of family genetic risk scores (FGRS; personalized measures of genetic risk inferred from diagnoses in relatives) across ten psychiatric disorders: major depression, anxiety disorders, obsessive-compulsive disorder, bipolar disorder, schizophrenia, anorexia nervosa, alcohol use disorder, drug use disorder, ADHD, and autism-spectrum disorder. Individuals who divorced had elevated FGRS across all disorders compared to those who were stably married or never married. FGRS for all disorders were higher among divorced females compared to divorced males; among those who did not go on to have a stable second marriage compared to those who had a stable second marriage; and increased as the cumulative number of divorces increased. In summary, genetic predispositions for psychiatric disorders are associated with the propensity to divorce, and with several differences as a function of sex, remarriage, and the cumulative number of divorce transitions.
More Related Videos
Related Concept Videos
Human Genetics
The complex relationship between genetics and psychology is observable through common biological components such...
Behavioral Genetics and Its Designs
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
Cancer Prevention
Some...
Psychological and Sociocultural Causes of Schizophrenia
Relative Risk
Pedigree Analysis


