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Updated: Jul 17, 2026

Conscious and Non-conscious Representations of Emotional Faces in Asperger's Syndrome
Published on: July 31, 2016
Connectivity patterns evoked by fearful faces demonstrate reduced flexibility across a shared dimension of adolescent
N A Hubbard1,2, R P Auerbach3, V Siless4,5
1Massachusetts Institute of Technology, Department of Brain and Cognitive Science and McGovern Institute for Brain Research, Cambridge, MA.
Abstract:
Adolescents experiencing anxiety or depression exhibit cognitive biases favoring the processing of negative emotional information. It remains unknown whether common neurobiological processes underlie these biases across anxiety and depression. Here, brain imaging was acquired from typical, anxious, and depressed adolescents during an emotional interference task. Functional connectivity patterns were assessed while adolescents were cued to attend to or ignore faces. Results revealed a shared dimension of anxious and depressive symptoms was associated with reduced changes in connectivity patterns between conditions wherein adolescents needed to ignore or attend to fearful faces. These findings were exclusive to fearful faces and only observed for functional connections with a primary face-representation area (fusiform gyrus). Results suggested a failure to flexibly adapt communication patterns with sensory representation areas in the presence of negative emotional information, which may reflect a common neurobiological mechanism explaining biases favoring such information shared amongst adolescent anxiety and depression.
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