Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

46
Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
46
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

460
Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
460
Positive Symptoms Schizophrenia: Hallucinations and Delusions01:26

Positive Symptoms Schizophrenia: Hallucinations and Delusions

50
Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...
50
Hallucinogens and Psychedelics01:27

Hallucinogens and Psychedelics

156
Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
156
Lateralization01:28

Lateralization

306
Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.
306
Cerebral Hemispheres01:05

Cerebral Hemispheres

299
The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...
299

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of Betanin on Key Enzymes Related to Obesity, Diabetes, Insulin Signaling Pathway, and Metabolic Disorders: In Vitro, Cellular, and In Silico Study.

Pharmaceuticals (Basel, Switzerland)·2026
Same author

A Comparative Study of Surgical and Endoscopic Gastrostomy Tube Insertion in Pediatric Patients.

Cureus·2026
Same author

Simulation-based and clinical training in undergraduate nuclear medicine education: evaluation of competency outcomes using a structured OSCE framework.

BMC medical education·2026
Same author

"A room of one's own": Exploring the role of delusions and social isolation on disorganisation in thought disorder.

Social psychiatry and psychiatric epidemiology·2026
Same author

Two-year delayed reconstruction of chronic distal biceps tendon rupture with allograft: a case report.

Journal of surgical case reports·2026
Same author

Sex-specific effect of cortisol on cerebral glucose metabolism across Alzheimer's disease spectrum: a neuroimaging study.

Frontiers in neurology·2026

Related Experiment Video

Updated: Jun 6, 2025

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
07:30

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

6.5K

Exploring the relationship between hallucination proneness and brain morphology.

Abdullah M Alotaibi1, Manal H Alosaimi2, Nawal S Alshammari3

  • 1Research Centre, King Fahad Medical City, Riyadh, 12231, Saudi Arabia; Clinical and Cognitive Neuroscience Group, Department of Experimental Psychology, Liverpool University, L69 7ZA, Liverpool, L69 7ZX, UK.

Neuroimage
|November 25, 2024
PubMed
Summary

Higher brain volumes in language areas like the superior temporal gyrus and Broca's area are linked to increased hallucination proneness in students. This finding contrasts with clinical studies showing volume reductions.

Keywords:
Brain structureBrain volumeHallucinationsLanguage-related areasThe continuum hypothesis

More Related Videos

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
08:29

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Published on: December 18, 2016

14.0K
Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease
09:06

Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease

Published on: June 9, 2018

12.1K

Related Experiment Videos

Last Updated: Jun 6, 2025

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
07:30

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

6.5K
Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
08:29

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Published on: December 18, 2016

14.0K
Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease
09:06

Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease

Published on: June 9, 2018

12.1K

Area of Science:

  • Neuroscience
  • Cognitive Psychology

Background:

  • Hallucinations are linked to brain structure changes, especially in language cortical areas.
  • Existing models on brain volume and hallucination proneness lack substantial empirical support.

Purpose of the Study:

  • To investigate the relationship between hallucination proneness and brain volume in specific language-related cortical regions.
  • To examine auditory and visual hallucination proneness in relation to superior temporal gyrus and Broca's area volumes.

Main Methods:

  • Assessed hallucination proneness using the Launay-Slade Hallucination Scale (LSHS) in 68 university students.
  • Measured brain volume in the superior temporal gyrus and Broca's area using structural MRI scans.

Main Results:

  • Found significant positive correlations between LSHS scores and brain volume in the superior temporal gyrus and Broca's area.
  • Individuals with higher hallucination proneness showed larger brain volumes in these language regions compared to low-proneness individuals.

Conclusions:

  • Higher brain volumes in language areas may correlate with increased hallucination proneness in non-clinical populations.
  • This finding challenges existing models and suggests a complex relationship between brain structure and hallucinatory experiences.