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Generation of Alginate Microspheres for Biomedical Applications
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Design, synthesis and biological evaluation of alginate oligosaccharide derivatives

Wenkang Guo1, Manchun Chen2, Changjie Zou3

  • 1School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230000, China; Yangtze Delta Drug Advanced Research Institute and Yangtze Delta Pharmaceutical College, Nantong 226133, China; Haitang (Jiangsu) Biotechnology Co, Ltd, Nantong 226133, China.

Bioorganic & Medicinal Chemistry Letters
|November 25, 2024
PubMed

Keywords:
Acute kidney injuryAlginate oligosaccharideAlginate oligosaccharide derivatives

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Oligosaccharide Assembly01:24

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Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
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