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Relationship Between Screening-Detected Atrial Fibrillation and Blood Pressure Levels in Elderly Hypertensive

Keitaro Senoo1,2, Mitsuko Nakata3, Arito Yukawa1

  • 1Department of Cardiac Arrhythmia Research and Innovation, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Thrombosis and Haemostasis
|November 25, 2024
PubMed

Insights

Screening detected atrial fibrillation (AF) in 5.8% of elderly hypertensive patients. Blood pressure levels did not significantly impact AF detection rates in this population.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Atrial Fibrillation Screening

Background:

  • Hypertension is a known risk factor for atrial fibrillation (AF) and strokes.
  • Limited data exists on screening-detected AF in hypertensive individuals and its correlation with blood pressure (BP).
  • Early detection of AF is crucial for stroke prevention.

Purpose of the Study:

  • To investigate the prevalence of screening-detected AF in elderly hypertensive patients.
  • To assess the relationship between baseline blood pressure categories and AF detection rates.
  • To evaluate the impact of measurement adherence and antihypertensive medication on AF detection.

Main Methods:

  • Prospective, decentralized clinical trial involving 4,078 hypertensive patients (≥60 years) across Japan.
  • Participants used home BP monitors with ECG capabilities for 3 months.
  • Analysis included baseline BP, AF detection rates, and time to detection.

Main Results:

  • Undiagnosed AF was detected in 5.8% of participants (220/3,820).
  • AF detection rates did not significantly differ across baseline BP categories (log rank test, p=0.54).
  • Measurement rates and antihypertensive drugs did not significantly affect AF detection.

Conclusions:

  • Screening identified undiagnosed AF in 5.8% of elderly hypertensive patients.
  • Baseline blood pressure levels were not significantly associated with AF detection.
  • Home monitoring is effective for detecting AF in this population, irrespective of BP control.

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