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Updated: Jun 6, 2025

Individualized Reconstitution of Human Milk Microbiota: A Feasible Approach in Real-World Settings
Published on: February 7, 2025
[Interpretation of key points from the "Expert Consensus on Diagnosis and Management of Neonatal Cow Milk Protein
Xin-Yin Zhang1, Li-Ting Liu1, Lei Bao1
1Children's Hospital of Chongqing Medical University/National Clinical Medical Research Center of Child Health and Disease/Key Laboratory of Developmental Diseases of Children of Ministry of Education/Chongqing Key Laboratory of Metabolic and Inflammatory Diseases of Children, Chongqing 401122, China.
Abstract:
The clinical manifestations of cow's milk protein allergy (CMPA) in neonates are non-specific and involve multiple organ systems. CMPA may also adversely affect physical growth and central nervous system development in neonates, lead to functional disorders, and increase anxiety and stress among family members. Due to the lack of specific clinical manifestations and diagnostic methods, the diagnosis and management of CMPA in neonates continue to pose significant clinical challenges. To facilitate standardized diagnosis and treatment of CMPA in neonates, the Neonatology Group of the Pediatric Branch of the Chinese Medical Association and the Editorial Committee of the Chinese Journal of Pediatrics have jointly developed the "Expert Consensus on Diagnosis and Management of Neonatal Cow's Milk Protein Allergy (2023)". This article presents and interprets the key points of the consensus regarding dietary and nutritional management of CMPA in neonates.
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