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Beyond Awareness: Hope for a CMV Vaccine! An Introduction to the Conference, "CMV Vaccine Development-How Close Are
Megan H Pesch1, Mark R Schleiss2, Stanley A Plotkin3
1Division of Developmental and Behavioral Pediatrics, University of Michigan, Ann Arbor, MI 48109, USA.
Congenital cytomegalovirus (cCMV) is a leading cause of childhood disability. Progress is being made on a pre-conception vaccine to protect women of child-bearing age and reduce cCMV disease burden.
Area of Science:
- Virology
- Immunology
- Vaccinology
Background:
- Congenital cytomegalovirus (cCMV) is the primary infectious cause of congenital disabilities in newborns.
- Significant public health burden associated with cCMV, impacting neurological development and hearing.
Framework:
- Focus on developing a pre-conception CMV vaccine for women of child-bearing age.
- Workshop convened by the National Institute of Allergy and Infectious Diseases (NIAID) to assess CMV vaccine development progress.
Implementation:
- Keynote presentation by Dr. Megan Pesch (National CMV Foundation) highlighted the urgent need for a cCMV vaccine.
- Discussion centered on advancements in vaccine candidates and strategies for protective immunity.
Implications:
- A successful CMV vaccine could significantly decrease the incidence of cCMV-related disabilities.
- Potential benefits extend to other vulnerable populations, including transplant recipients.
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