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Rio Mamore Hantavirus Endemicity, Peruvian Amazon, 2020
Emerging Infectious Diseases
|November 26, 2024
Summary
Hantavirus infection was detected in Peru, with Rio Mamore hantavirus identified in the Amazon. Further surveillance is crucial for understanding hantavirus patterns in Latin America.
Area of Science:
- Virology
- Infectious Diseases
- Epidemiology
Background:
- Hantavirus infections pose a significant public health concern in Latin America.
- Understanding regional hantavirus epidemiology is essential for effective disease control.
Purpose of the Study:
- To investigate hantavirus infection patterns in febrile patients in Peru.
- To identify circulating hantavirus species and assess seroprevalence.
Main Methods:
- Molecular detection using reverse transcription PCR (RT-PCR).
- Serological assays including IgM and IgG ELISA and immunofluorescence assay (IFA).
- Genomic sequencing and phylogenetic analysis.
Main Results:
- Rio Mamore hantavirus was identified in a patient from the Peruvian Amazon, indicating endemicity.
- A hantavirus incidence of 0.5% was observed in Loreto, with reactivity to Sin Nombre virus (SNV) and Andes virus (ANDV).
- Overall IgG reactivity was 1.7% across Peru, suggesting diverse New World hantavirus circulation.
Conclusions:
- The study confirms the presence of Rio Mamore hantavirus in Peru and suggests endemic circulation.
- Findings highlight the need for enhanced hantavirus diagnostics and surveillance in Peru and Latin America.
- Circulation of antigenically distinct hantaviruses warrants further investigation.
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