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Updated: Aug 10, 2026

Characterization of Molecular Mechanisms of In vivo UVR Induced Cataract
Published on: November 28, 2012
[Dose-effect relationship based on frequency of occurrence of radiation cataracts]
Abstract:
The paper is concerned with the results of experiments on random bred mice concerning dose-effect relationship estimated by radiation cataract developing 1 year after x-ray irradiation at doses of 0.05, 0.5, 4, 7 and 10 Gy. It was shown that the effect of ionizing radiation on the lens registered by its opacity, could be threshold-free and described with the equation of the straight line. The authors found it appropriate to introduce a concept of a permissible risk dose causing a certain degree of cataract. In their opinion, the existing maximum tolerance radiation dose based on the absence of cataract at doses less than 7.5 Gy, should be lowered not less than by one order.
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