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Updated: Jun 6, 2025

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
Dysphagia in Mexican older adults with mild cognitive impairment and dementia
Georgina Martínez-Peña1, Alberto J Mimenza-Alvarado1, Lourdes M Ávila-Escobedo2
1Department of Geriatrics, Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán".
Introduction:
Dysphagia and cognitive impairment are common in older people. It is linked to alterations in brain areas related to swallowing.
Objective:
To explore the characteristics of dysphagia using fluoroscopy in patients with mild cognitive impairment (MCI) and dementia.
Material And Methods:
158 participants from a memory clinic. Specific criteria for MCI and dementia were used. Dysphagia was assessed with EAT-10 (≥ 3). Those who accepted completed a fluoroscopy study with a barium swallow to evaluate the phases of swallowing; the presence of bronchoaspiration supported the diagnosis of dysphagia. A logistic regression analysis was performed to test the probability between dysphagia and MCI.
Results:
According to EAT-10, 86 (54.4 %) were at risk of dysphagia, confirmed in 84 by fluoroscopy, 53.8 % MCI group and 46.2 % dementia. An inverse association was observed in the MCI oral phase group (OR 0.23, p < 0.025), and a positive association; in protection phase against regurgitation (OR 3.76, p < 0.056) and laryngeal muscle contraction (OR 3.22, p < 0.045) versus dementia group.
Conclusions:
The study showed a high frequency of dysphagia in patients with MCI, this highlights the importance of its early detection to improve complications associated with dysphagia.
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